Abstract: The article aims at a question that how to improve fracture conductivity with high closure stress. It researches the influences of contact time between acid and rock, types of acid, closure stress on conductivity respectively and how to improve conductivity by compound manner. It turned out that flow conductivity has a linear relationship with closure stress on semilog coordinate in same contract time between acid and rock, which means higher closure stress, lower flow conductivity. The experimental results also show that acid etching fracture has higher flow conducti-vity with big propping agent in low closure stress. It's more appropriate to choose propping agent from 40 to 70 mesh in high closure stress stratum, and the larger the sanding concentration, the higher the flow conductivity. Therefore, sanding in the acid etching stratum is one of the most effective means for improving flow conductivity.